Pharmaceutical Name: DNP
Chemical Name: 2,4 Dinitrophenol
Presentation: 100 mg capsules – 100 capsules per pouch
Click here for B3s Labs DNP 50 Capsules
Estrogenic Activity: None
Progestational Activity: None
DNP 7 days cycle: the first 3 days - 200 mg per day;
the next 4 days - 400 mg per day (which means you should take 400 mg for 4 days).
Our DNP is NOT manufactured by an underground lab. Our DNP is manufactured by well-known legitimate medical firm which sells Chemical Substances to nationwide.
2,4-Dinitrophenol, more commonly known as DNP, is a solid yellow crystaline that has a sweet, musty odor. It is a manufactured chemical that does not occur naturally in the environment.
2,4-Dinitrophenol (DNP) has many uses, 2,4-dinitrophenol is most notorious as a dangerous yet effective weight loss agent and fat burner in the hardcore underground bodybuilding supplement industry.
2,4-Dinitrophenol DNP In The World Of Bodybuilding
Originally used as an ignitor for TNT as well as a pesticide, researchers at Stanford University discovered that DNP causes weight loss in 1933. The late pioneer bodybuilding Dan Duchaine wrote about DNP for fat reducing weight loss and DNP has been used in the hardcore bodybuilding underground for fat and weight loss for decades.
Compared to other thermogenic, fat reducing, and weight loss agents such as the epederine/caffeine/aspirin (ECA) stack would boost the user's metabolism 3% or the Clenbuterol/Cytomel T-3 stack which would boost metabolism 5-10%, DNP was seen to raise metabolism up to a relatively controlled 50% making DNP a seemingly miracle supplement. While clen/t-3, ECA, and others significantly raised the body's temperature, DNP raised internal temperature 2-4 degrees F.
The main problem with DNP is its severe side effects. Exercise during a DNP cycle should be kept to light workouts. DNP has not been seen to cause cancer, but death is a posibility if DNP raises the user's body temperature too high as there is not limit to how hot DNP can make the user's body. The lethal dose of DNP is only 4 times the dose that is effective in losing weight and fat loss.
DNP is not an appetite suppressant, so a user will be hungry, and DNP users will especially crave carbohydrates due to glucose inefficiency. Some users may be allergic, and less than 1% of women who used DNP in the 1930's for fat reducing and weight loss developed cataracts which led to the 1938 FDA 2,4-dinitrophenol DNP ban as a weight loss drug.
DNP since has been used off and on with scrutiny from within and outside the bodybuilding industry. Protesters of DNP note that DNP is not a forgiving chemical. Understanding what the effects, risks, and limitations of the substance are before trying to acquire and use DNP promote their hopes to deter potential DNP users, but the effectiveness of DNP to help with fat reduction and ultimately weight loss is hard to deny. A danger is the fact that DNP has a cumulative effect with a 36-hour half-life. DNP takes up to 48 hours to flush from a user's system. Many bodybuilders adapt the "more is better" theory to their use of DNP severely increasing their risk of harmful side effects and possibly death.
Weight Loss with DNP - Scientifically Speaking
DNP accomplishes the astounding boost in metabolic rate via inhibition of the F0F1 ATP synthase molecule, located in the inner wall of each mitochondrion. While the electron transport chain still functions to pump hydrogen ions into the inter-membrane space, the coupling of the proton gradient to ATP production is rendered impossible by DNP. As a result, ATP production is dramatically reduced, and the energy is instead thrown off as heat. This results in an astounding production of heat; when using dinitrophenol, the athlete will radiate so much heat that it is uncomfortable to be within any proximity of them. Luckily, this heat does not fully contribute to body temperature increases, and is instead thrown off from the entire body surface, particularly the head. As a result, adequate doses of DNP will usually only elevate body temperature by about 1-1.5?C. This is a good thing for your central nervous system and other delicate tissues. If the heat produced by ATP contributed in a more direct matter to body temperature, effective doses for fat loss would cause body temperature increase. Nonetheless, overheating is a very real danger.
Under these conditions, much of the food that we eat could not be used for ATP synthesis and we lose weight. However, too much inhibitor and we could make too little ATP for life. The difference between weight loss and death is only a small concentration change in dinitrophenol, making the drug dangerous. Simply put, this means that while eating your normal diet, you will have somewhere between 20% and 40% reduction of calories.
Risks of using 2,4-Dinitrophenol DNP for Weight Loss
Hearing all of these wonderful things probably has you wondering what the side effects and risks are. They are quite formidable and contribute to making DNP one of the most intolerable (though effective) drugs used in bodybuilding.
CONSUMING DNP FOR WEIGHT LOSS PURPOSES IS NOT RECOMMENDED WHATSOEVER, but if you are exposed to it, you suffer any of these side effects, and they are extremely bothersome, it is the recommendation to cease contact immediately and see your physician as soon as possible. Do not attempt to continue the exposure at that point.
Safe and Effective DNP Dosage...
...at least as safe as it gets when using DNP for weight loss. Dosing is highly individualized and most generalizations tend to collapse quite quickly. As a result, none will be attempted. Start on the low end of the scale and see how you react. It is not recommended to take more than 300mg at any one time.
Getting the right dosage of DNP is rather easy to do although the importance of proper dosage cannot be overstated. It is far better for one to err on the side of too little rather than too much, certainly in the case of the novice who does not know if they are allergic to the substance.
As stated before, the commonly used dosage by bodybuilders and other reasonably lean persons is 4-6mg/kg of bodyweight. This would mean that a 100-kilogram bodybuilder would use anywhere from 400-600 mg per day. Experienced users commonly are found using up to 800mg/day relatively safely, and beginners sometimes find that they enjoy 3-5 pounds of fat loss per week with as little as 200mg/day.
So, a person weighing 200 lbs would weigh about 91 kg. So 4mgs per kg of body weight would be the equivalent of 364 mgs of DNP per day. Since DNP comes in 200 mg capsules, the user would take one cap twice daily to stay within range. The lethal dose is a mere 32mg/kg...only 4 times the max effective dose of 800mg/day. The addage "more is better" does not ring true in this case. Heed the warning!
DNP should be taken in 8 to 12-day cycles to avoid liver and kidney damage and to allow your muscles to recover. Bodybuilders typically look their best 48 to 96 hours after cessation of usage. A 10-day cycle of 400mg per day (200mg twice daily) would be a typical effective dose for a 225lb man. This allows for a total of two weeks from start to finish with a 4-day recovery period. Positive results have been seen with a lower dose, but conversely, better results have been achieved safely with a higher dose. Positive results have been seen in users taking 200mg to 800mg per day. Keep the formula of 4-6mg/kg of body weight in mind.
Since DNP has this inhibiting effect, glycolosis is inhibited as well, causing a diabetic effect due to the conversion of glucose without insulin, so you may have heard that people take insulin with DNP. This will counter act the symptoms of lethargy and lack of energy due to DNP's use. Other supplementation is also suggested to limit side effects as stated later in this column.
Timetable of Effects and Symptoms of a DNP Cycle
DNP CYCLE Day 1 -None; possibly elevated carbohydrate cravings and/or temperature elevation.
DNP CYCLE Day 2 - T4-T3 conversion has begun to decrease; lethargy possible. Temperature should be elevated, and radiation of heat is noticeable.
DNP CYCLE Days 3-5 - Body temperature is elevated, with all the effects that one expects from DNP use. In addition, water retention usually becomes manifest here.
DNP CYCLE Days 6-10 - Definite water retention, along with other symptoms of use; user most likely feels fatter due to having "flatter" muscles (mainly the result of glycogen depletion) and holding water. Final DNP dose taken in the evening of Day 10.
DNP CYCLE Days 11-12 - DNP is clearing the system slowly. All symptoms are still present.
DNP CYCLE Days 13-14 - Water should be gone by now, or getting there. Mild diuretics will expedite this. The user will probably notice perceived greater cardiovascular and muscular endurance.
96 Hours After Final Dose - This is when someone tends to look their best. Their glycogen stores are usually compensated at this point and the retained water should be gone.
Taken from Gym Magazine
DNP was used extensively in the 1930s in diet pills after Cutting and Tainter at Stanford University made their first report on the drug's ability to greatly increase metabolic rate. DNP acts as a protonophore in the mitochondrial membrane, uncoupling oxidative phosphorylation and making ATP energy production less efficient. In effect, part of the energy that is normally produced from cellular respiration is wasted as heat. This inefficiency is proportional to the dose of DNP that is taken. Thus, as the dose increases and energy production is made less efficient, the metabolic rate is increased (and more fat is burned) in order to compensate for the inefficiency and meet energy demands. Interestingly, the factor that limits ever increasing doses of DNP is not a lack of ATP energy production, but rather an excessive rise in body temperature due to the heat produced during uncoupling. Accordingly, DNP overdose will cause a fatal fever. Studies have shown that an acute administration of 20-50 mg/kg in humans is lethal. Concerns about dangerous side-effects and rapidly developing cataracts resulted in DNP being discontinued in the United States by the end of 1938. DNP, however, continues to be sold on the internet illegally, targeting bodybuilders and athletes who want to rapidly lose body fat. Fatal overdoses are reported on occasion.
Some advocates of the drug advise people to take doses of 5-8 mg/kg daily. It's commonly advised, however, that the dose be slowly titrated according to personal tolerance, which varies greatly.
There is limited and conflicting data on the pharmacokinetics of DNP in humans. The EPA states that "Data on the elimination kinetics of the dinitrophenols or their metabolic products in humans were not found." The ATSDR's Toxicological Profile for Dinitrophenols also states that "No studies were located regarding distribution in humans after oral exposure to 2,4-DNP. Limited information is available regarding distribution in animals after oral exposure to 2,4-DNP." However, they do state that "Elimination from the body appears to be rapid, except possibly in cases of compromised liver function." This conincides with a review in the NEJM on the biological actions of dinitrophenol, which stated that "Judging from the metabolic response, DNP appears to be eliminated entirely in three or four days in the presence of liver or kidney damage it is possible that the drug will be retained over a longer period." Oddly, more recent papers give an array of possible half-lives, ranging from 3 hours, to 5-14 days. Other recent papers maintain that the half-life in humans is unknown.
In a study on mice, a lethal dose of 35 mg/kg decreased to 5 mg/kg body weight when the environmental temperature was raised to 39 C (102.2 F). As the ambient temperature increases, so does the risk of overheating. People who use increased ambient temperatures for weight-loss, such as wrestlers and runners, are potentially at greater risk of overdose.
Although further investigation is needed, dinitrophenol-induced hyperthermia has been successfully resolved with dantrolene administration. "Dinitrophenol uncouples oxidative phosphorylation, causes release of calcium from mitochondrial stores and prevents calcium re-uptake. This leads to free intracellular calcium and causes muscle contraction and hyperthermia. Dantrolene inhibits calcium release from the sarcoplasmic reticulum which reduces intracellular calcium. The resulting muscle relaxation allows heat dissipation. There is little risk to dantrolene administration. Since dantrolene may be effective in reducing hyperthermia caused by agents that inhibit oxidative phosphorylation, early administration may improve outcome."
While DNP itself is considered by many to be too risky for human use, its mechanism of action remains under investigation as a potential approach for treating obesity. Currently, research is being conducted on uncoupling proteins naturally found in humans.
Hearing all of these wonderful things probably has you wondering what the side effects and risks are. They are quite formidable and contribute to making DNP one of the most intolerable (though effective) drugs used in bodybuilding. Starting with the most significant, and descending in importance, are the following risks and side effects of DNP use.
Risks of DNP
Overheating: There is no upper limit to DNP's body temperature increase, meaning that one may literally "cook from the inside" if they take too much. Dosage considerations will be given later, but even an overdose of 4-6 times the recommended dosage may be lethal. Much smaller overdoses may result in damage to the brain and/or other body systems.
Carcinogenesis: Phenols in general are reputed to be carcinogenic. Although 2,4-dinitrophenol has never been implicated in a cancer diagnosis, some are nonetheless concerned, and understandably so. In addition to the inherent carcinogenic potential caused by its status as a phenol, production of free radicals and the release of various compounds stored in adipose tissue stores during DNP's rapid oxidation of fat may also potentially be harmful.
Death: This is self-explanatory and has occurred with several bodybuilders who chose to use this compound.
Side Effects of DNP
Discomfort and sweating: This is the single most noticeable effect of DNP use, both by the user and those around him/her. Even in the winter, while indoors at ambient temperatures, one may expect his or her shirt to be completely soaked through with sweat. Those with jobs requiring formal or semi-formal apparel are advised to consider other means of fat loss (or a new job, if preferred). Other obvious considerations lie in the areas of social life, personal appearance, etc. and the user must prioritize.
Insomnia: Second in frequency of reports to sweating and discomfort is insomnia this may be at least partially attributed to discomfort. Possible means of countering this include such supplements as Valerian root or melatonin. Alternatively, one may deal with this via prescription or OTC sleep medications or GHB-A precursors. However, these may be addictive if used on a regular basis and if their use may be avoided, by all means abstain from using them.
Yellow bodily fluids: Some don't notice this, but others find that all of their bodily fluids take on a yellowish appearance. Urine is a darker yellow, and even semen and vaginal secretions may be affected. According to current knowledge, this is not known to be harmful in and of itself.
Muscle Soreness: This is yet another thing that may be minimized via cerebral function. Dan Duchaine has recommended using a weight such as to allow no fewer than 15 reps per set of any weight training workout judging from anecdotal reports and personal experience, this seems to be good advice. Low levels of ATP are a cause of muscle soreness in and of itself the additional factor of encumbered recovery mechanisms make extreme soreness (and if not careful, catabolism) quite possible.
Allergic Reactions: These are highly individualized but may be summarily discussed. Various reactions are common with DNP use, and approximately 10% of users will be extremely allergic to it. Allergic reactions can include hives, blisters, and/or inexplicable rashes. If you suffer any of these side effects, and they are extremely bothersome, it is the recommendation of the author to cease usage immediately. If so desired, another trial may be made at a later date with a lower dosage, but do not attempt to continue the drug cycle at that point.
Carbohydrate Cravings: To counter this, some methods will be touched on later. As with most diets, willpower is sometimes the single most important factor.
All of this tells me that your body will need to create more energy than usual to keep up with the demands DNP is placing on it. In addition, it will have to use more of the food you take in to produce that much-needed energy, and less of that food to create and store fat. In fact, you will start using stored fat as energy to attenuate the energy deficit DNP creates. I have seen studies on animals where a +60% increase in metabolic rate is achieved with DNP use , although I feel that in humans, the rate may actually be higher. My speculation is that proper DNP use in humans can net a 40-80% rise in BMR (basal metabolic rate). This is all from hypermetabolism, or the increase in metabolism or your bodys need to use more energy to perform tasks.
So what happens when your body requires more energy to do today the same things it did yesterday? You lose more fat today than you did yesterday. In this case, a lot more. What else? You get tired more quickly as your body struggles to convert food into energy. Your endurance will suffer. Your staying power in the last few reps of a set will vanish. Your ability to complete the same amount of sets as you did yesterday, with the same intensity and weights will suffer. But that wont seem like much of a big deal to you at the time, because you probably wont get much of a "pump" at all from the workouts you are completing because DNP reduces the amount of available glycogen in your muscles. DNP will also increase your rate of ventilation, as your lungs try to get oxygen into your muscles . Your blood will be moving a bit slower than usual, as DNP will increase the viscosity (thickness) of it. Basically, it will increase your bodys need for oxygen as well as your blood viscosity, and it nearly doubles the rate of oxygen consumption in muscles. Thus, your body will have to work much harder to oxygenate your blood, and then transport it to working muscles. Cardiac output will then increase proportion to this new rate of oxygen consumption .If you are an athlete, you will play like garbage on DNP because of all that stuff I just mentioned. For these reasons, I see it as very useful for a bodybuilder (who only has aesthetics to be worried about, not functional ability or performance), but not very useful for an athlete. If (and this is a big if), you are badly out of shape and fat before you have training camp for your sport´s preseason, then I suppose you can try to use this stuff to lose some fast weight. But in all honesty, a 20 day cycle of DNP, no less than a month away from training camp is all Id risk. You will lose some weight, and only have to keep it off for a month until training camp starts. I really want to stress, though, that this stuff is an exceptionally poor choice for use by an athlete. And remember that part I told you about earlier, about DNP inhibiting muscle contraction?
Speaking about getting weaker, DNP will lower Thyroid (T3) and Thyroid Stimulating Hormone levels. Lower thyroid levels are positively correlated with lethargy (tiredness) and muscle weakness. So its pretty fair to say that just as DNP makes you lose fat via several mechanisms, it is just as fair to say that it will make you feel like garbage through several mechanisms. Do not get me wrong, not everyone feels like total garbage on DNP, but it is by far the most common side effect I have heard of, next to bad breath. No, really. Oh, and I almost forgot yellow(ish?) sweat and body odor that is brutal. Then there is this weird taste in your mouth .On the bright side, we are talking about fat loss of almost a half a kilogram per day (1lb/day), when DNP is properly used.
One of the most worrying side effect of DNP use is it is ability to cause vision problems. Realistically, you should be alright if you keep your doses and duration of use reasonable.
A lot of the side effects (at least the more dangerous ones, including the ones associated with vision problems) need to be addressed before I tell you how much DNP you can use, and for how long. First of all, you will want to make sure you are taking in enough carbs. Yeah, that is right, a ketogenic diet (that is a diet with no carbs, essentially) is too dangerous to consider with DNP use. In fact, I recommend taking in a good amount of carbs after your workouts, at least 1-2g/kg of bodyweight. Glucose metabolism is enhanced in less than a week, and I am wary of depriving your body of carbs while using DNP. All of these extra carbs are going to make you sweat more, as your body literally burns them up. Id still say you can take in as many carbs as you want& and you will want a lot (carb-cravings are a side effect of DNP use).
The other thing you want to use is pyruvate, which at the very least will have occularprotective properties (yes, I made that word up, and it means something that protects your eyes). Pyruvate will also have some other cool effects on your bodys energy production ability, but here, we are primarily concerned with not developing cataracts or floaters in our vision.
Thankfully, DNP is not particularly hard on your heart, blood pressure, or liver. The only reason you will experience increases in cardiac output is as a response to the increased ventilation DNP will cause while you are exerting any kind of muscular force, and even then it is not particularly dangerous. Most DNP users feel this effect only vaguely, certainly nothing compared to what would be experienced with use of Ephedrine or maybe even caffeine. So we are really only dealing with the lowering of thyroid values and the possible eyesight problems. Oh and that pesky "death thing"
So far, we know we need to keep some carbs in our body, and take some pyruvate. I can only assume you will also be taking a multivitamin/mineral while using DNP, just to keep all of our bases covered. There is also some good reasons to take an energy supplement with DNP use, since it will sap energy out of you. I recommend something in the morning, and pre-workout, as a minimal insurance against feeling too tired all the time. Also, you want to take some T3 with your DNP, because of DNP´s aforementioned ability to lower conversion of T4 into T3, 50-100mcgs/day should suffice. Taurine and potassium are popular additions to a DNP cycle for many experienced users and they may not help, but if cramping becomes an issue, then they could help. Because wed never even consider using DNP and not taking in enough water, right? Id suggest water intake be kept obscenely high, and as close to two gallons per day as you can get.
So now that you know all about DNP, and how to avoid most of the negative side effects, I will tell you how much to take. From my research, Id say 2mgs/kg-5mgs/kg is optimal. If I were going to use this stuff personally, Id stay on the low end of that, but I am aware that the "Underground Standard" is 600mgs/day. That is still a reasonably safe dose, for most. I will also say that were I to personally use DNP, I would limit its use to less than 3 weeks, 20 days is the longest I am comfortable recommending.
The 7-day DNP fat loss cycle:
The 7-day DNP fat loss cycle involves a moderate to high dosage of DNP for fat burning. The DNP fat loss involves a 7-day on, 7-day off approach with four distinct phases. Most athletes using DNP follow this type of cycle. The phases are as follows:
Phase 1: The 3-day Carb-Depletion Phase.
Phase 2: The 1-day Thyroxine (T3) Re-normalization Phase.
Phase 3: The 14-day DNP Inferno Phase.
Phase 4: The 2-day Post-DNP Phase.
Phase 1. The 3-day Carb-depletion phase
Phase One has a three-day duration and begins the four days preceding the ingestion of DNP. The purpose of this phase is to deplete muscle-glycogen content by restricting carbohydrates. This is achieved through a Ketogenic style diet.
Kcals should be restricted to 10-12 times bodyweight in lbs. And carbohydrates should be restricted to less than 60g/day. Protein is consumed at 1 gram per pound of bodyweight or higher and the remaining dietary calories should come from fat.
This phase lasts exactly 3 days, and will reduce muscle-glycogen levels so that the body is forced to rely on fat as fuel more readily when you start your DNP cycle.
Phase 2 The 1-day Thyroxine (T3) Re-normalization Phase
This is a new concept for DNP dieting. During the past three days, the athlete has restricted carbohydrates and as a direct consequence T4-T3 conversion is slowed down resulting in reduced T3 levels. This is bad for the DNP phase, as you need enough active T3 to last throughout the entire 7-day on DNP phase.
Day four of the DNP cycle involves a mega-carbohydrate meal at mid-afternoon (4-6PM) designed to create a massive insulin spike and re-normalize T4-T3. This concept has been extrapolated from ketogenic diets and has been shown to dramatically increase serum concentrations of T3.
Day 4 involves Keto eating until the Mega-carb meal. Then in the late afternoon, at least circa 250g of carbohydrates must be consumed to create an insulin spike. Any sugar (fructose, sucrose, maltose etc.) is fair game. Fructose in particular is good because it primarily re-fills liver glycogen which is directly involved in T4-T3 conversion. (Empty liver glycogen signals the thyroid to decrease T4-T3 conversion).
As a side-note, a 250g carb-meal after three days of Keto dieting creates a more pronounced insulin spike than would a 250g carb-meal after three days of normal eating.
Kcals during Phase 2 should be kept at 15X Bodyweight in lbs. Macro-nutrient break-downs can be calculated by the athlete. The only carb intake on day 4 should be the 250g carb-meal.
Phase 3 The 14-Day DNP Phase
The first two days of actual DNP consumption are the most important to follow correctly. During Days 1 and 2 of the actual DNP portion of the cycle, it must be determined if the athlete will have an allergic reaction to DNP.
Day 1: 200 mg of DNP is ingested
Day 2: 200 mg of DNP is ingested
At this point the dieter should be able to assess if an allergic reaction has occurred. A DNP-stimulated allergic reaction will lead to swelling in as little as 1 to 2 days time. Approximately 10% of athletes will have such a reaction. The unfortunate few who experience this type of a reaction must terminate the cycle immediately. Benadryl or Ketotifen (Anti-histamines) can be used to treat mild symptoms. Obviously a doctor should be consulted should the symptoms prove more severe.
Day 3: Dieters making it to day 3 of the DNP phase have the option of increasing their dosage. The normal dosage for beginners is 400mg DNP/day. Even an amount this small should provide outstanding results. A word of caution. DO NOT TAKE MORE, if you are not experienced with DNP-use. More advanced users may chose to go higher based on past experience.
The 400mg/day dosage is maintained from Day 3 through Day 9(Exactly 7 days). The last dose is taken on Day 9.
1. An ECA stack is beneficial while on a DNP cycle as it as it acts as an anorectant. DNP raises Neuro-peptide Y levels in the brain, which is directly linked to increased hunger. Consuming 75-100mg total of ephedrine alkaloids/day should be sufficient to suppress appetite. PPA (Nor-ephedrine) should NOT be used as it causes lethargy when combined with DNP.
2. Anti-oxidants. Due to the DNP induced rapid combustion of fats, free-radical production skyrockets up-wards. To combat this, anti-oxidants must be used. Anti-oxidants are the single most important supplement to take on a DNP cycle.
a) Fat-soluble Anti-O: Vitamin E: 1000mgs/day
b) Water-soluble Anti-O: Vitamin C: 2-3g/day
c) Alpha Lipoic acid: 600-1000mgs/day
Dual-anti-oxidant: BOTH fat & water-soluble actually re-cycles other anti-oxidants.
3. Glycerol: Although optional, glycerol is often consumed at 15ml's 3X/day. Glycerol increases hydration for many athletes.
No additional supplements are really required other than these three. All the rest you have read in various DNP articles are more for peace of mind than improved functionality. I consider them overkill.
4. Water: Not a supplement, but an absolute necessity.
DNP causes sweating and can be incredibly dehydrating. Dehydration is the NUMBER ONE cause of most DNP problems and deaths. Excessive dehydration results in over-heating. Dieters who do not replenish fluids properly while on a DNP cycle could die. The consensus among athletes is that at least two gallons of water must be consumed daily.
5. EAT FRUIT while on your DNP cycle.
Fruit for some reason has been found to greatly reduce the lethargy associated with a DNP cycle. It also has a high water content, therefore it helps to keep the dieter hydrated. Watermelon is an obvious recommendation.
6. Dietary intake: There are several schools of thought on this matter, but sticking to the old standard always works.
Kcals should be kept anywhere from 10-15X Bodyweight in lbs. Macro-nutrient break-downs should be kept at around 20% fat, 30% protein and 50% carbs. (Changing the ratios in favor of more carbs and protein w/ less fat will result in a more fat loss but nothing special. Also, remember that more carbohydrates means more heat.)
Take for example the 220 lb (100 kg) bodybuilder. He would consume anywhere from 2200 to 3300Kcal /day (Depending on his appetite control).
a) Do not under any circumstances consume alcohol or ANY type of diuretic while on a DNP cycle. Alcohol and diuretics will dehydrate you and can cause SERIOUS problems.
b) Do not remain in a hot environment without replenishing fluid loss due to perspiration. This too can also cause SERIOUS problems.
c) Do not begin with a high dosage of DNP if you are a novice. This is just asking for a trip to the ICU.
The half-life of 2,4 Dinitrophenol is 36 hours. So, after 36 hours, there is only 50% of the DNP remaining in your system. Therefore, 72 hours later 25% remains. Then 12.5% remains after 108 hours. After 5 days (120 hours), there's roughly 9% of the DNP left in your body that you had on Day 9. This DNP concentration is low-enough to allow you to begin Phase 4 of the cycle the 2-day Post-DNP phase without compromising glycogen synthesis rates. Kcals during Days 10-14 should remain the same as during days 3-9. Phase 4: The 2 day Post DNP Phase.
The whole purpose of this phase is to get muscle-glycogen levels back to normal. The Ketogenic carb-up can be used as a sort of template for this phase.
After Phases two and three, muscle-glycogen levels are depressed and need to be replenished.
Day 15: Carb-intake should be 7g/Kg of LBM (lean body mass = bodyweight minus body fat.) So assuming a 220 lb bodybuilder has 0% body fat, lol, he would consume 700 g of Carbs. Protein-intake remains at 1g/lb and fat is restricted as low as possible.
The focus on day 1 should be on High-GI foods like Fat-free Ice-cream and all the other non-fat high sugar desserts. Calories should be around 4000 for the 220-lb bodybuilder in other words, 18X bodyweight in lbs.
Drastically restricting fat is CRITICAL here, as the body is still burning fat for fuel as you replenish your glycogen stores. In essence, the dieter is still losing fat while carbing up.
Day 16: Muscle-glycogen has increased, so carb-intake should be decreased from day one?s 7g/Kg to only 5g/Kg of LBM. That would be 500g for our 220-lb bodybuilder. Protein is 1g/lb again. Fat remains as low as possible. Kcals for the dieter are reduced to 3000 Kcal range, or around 14X Bodyweight in lbs. The focus of Day 2 should be low-GI foods like vegetables, milk, lean meats etc.
Dieters feeling extremely nauseated or who vomit during a cycle should discontinue use immediately and not restart for at least 36 hours.
Dieters should carry a pocket thermometer at all times. If body temperature rises above 102 Fahrenheit then the dosage should be lowered or the cycles should be terminated. Additionally, the dieter should take a very cold bath to lower the temperature.
In addition to water, V8 juice should be consumed. Drinking gallons of water depletes the body of electrolytes pretty badly predisposing the dieter to shock, nausea, lethargy, and even death. V8 is the best for replenishing electrolytes as it contains 950mg of potassium per 8oz compared to Gatorade?s 35mg of potassium in 8oz.
Massive amounts of fruits and sweets should be consumed if one becomes nauseated or vomits - i.e. force feed yourself.
Dieters should never allow themselves to become overheated on a DNP cycle. Always stay next to a fan and keep the air conditioner on. Do not attempt a DNP cycle if you work out doors in a warm climate or another warm environment like a kitchen. Even at low doses this can build up and be potentially dangerous.
There are two versions of DNP - regular and crystalline. Know which one you are taking. When taking the crystalline DNP caps, never take more than 200mg at once if you've never used it before. Even if you are used to it, it is still much safer to spread the dosage throughout the day. Crystalline DNP is much faster acting and can rapidly elevate temperature.
One of the primary causes of muscle breakdown after a steroid cycle is suppressed TSH. Anabolic steroids suppress TSH, which in turn lowers T3 and T4 production by the thyroid gland. The reduction in TSH is one reason that anabolic steroids are such excellent muscle builders.
Soon after the completion of a steroid cycle, TSH up-regulates, which in turn super-stimulates the thyroid. This excess stimulation causes the thyroid to produce above normal levels of T3 and T4. This increase in thyroid hormones is highly catabolic and is the main reason why people lose muscle post-cycle.
Athletes have learned that they need to restrict T3 production post cycle to prevent muscle loss. A novel approach to achieving this goal is the use of DNP. About 80% of the bodys endogenous T3 is produced from the metabolically
inactive T4 to the metabolically active T3. The de-iodinase enzyme is responsible for this conversion. It literally cleaves off an iodine molecule.
By ingesting 200mg DNP/day, the athlete can correct the over stimulated Thyroid, returning T3 levels back to normal. DNP directly blocks the production of T3 from T4 via the de-iodinase enzyme.
As a bonus, the reduction in your ATP stores because of the DNP is counter acted by an increase in the oxidation of triglycerides as an energy source. The benefit is the elimination of any potential fat-gain from the low post-cycle testosterone levels. And as DNP is non-hormonal, it has no effect on HPTA recovery.
After cessation of DNP use post-cycle, the athlete will reap the benefits of the "Anabolic Rebound Effect" which further lends credence to the use of DNP as a post-cycle ancillary for the elimination of any post-cycle muscular losses.
200mg alpha lipoic acid 3x a day with meals
1200-1500mg magnesium in 2-3 divided doses.
2-3000mg vitamin C
1200IU of vitamin E
200mcg of selenium.
1000-2000mg of calcium (can?t take it with the magnesium, though. Take it before bed)
Melatonin if you can?t sleep and it is also one of the best and cheapest anti-oxidants.
50mg of zinc a day
one iron tab as hemoglobin is a protein as well.
A potassium gluconate tab or two a day
Taurine at 3g a day.
Glutamine at 15g-20g a day .
1 table spoon glycerol 3 x a day
at least 2 gallons of water
a fan to point at your head while sleeping- or at work- basically anytime you can point a fan at you
500mg grapeseed extract
300mg cranberry extract
600-900mg of green tea
a good mulit vitamin
EC+1g of tyrosine 3x per day and 20mg of yohimbine topically 2x per day- for added energy and fat burning effects.